Insulin-like growth factor-I and especially IGF-I variants are anabolic in dexamethasone-treated rats
IGF-1 Analogue
IGF-1 LR3
- Long R3 IGF-I LR3IGF-I
An 83-amino-acid recombinant analogue of human insulin-like growth factor 1, consisting of the 70-residue IGF-1 sequence with arginine substituted at position 3 and a 13-residue N-terminal extension, retaining three intrachain disulfide bonds.
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Compound information
Technical specifications
Description
An 83-amino-acid recombinant analogue of human insulin-like growth factor 1, consisting of the 70-residue IGF-1 sequence with arginine substituted at position 3 and a 13-residue N-terminal extension, retaining three intrachain disulfide bonds.
Molecular profile
- Type
- Recombinant IGF-1 analogue protein
- CAS number
- 143045-27-6
- Molecular weight
- ~9.1 kDa
- Molecular formula
- C400H623N111O115S9
- Amino acids
- 83
Storage requirements
Lyophilized (powder)
-20°C
Reconstituted
2-8°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Reconstitute with bacteriostatic water
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Sources & references
Published literature, listed for reference only. Nothing here describes an intended use of this product.
Design and characterisation of long-R3-insulin-like growth factor-I muteins which show resistance to pepsin digestion
Growth Factors 1996
View sourceEffect of recombinant porcine IGFBP-3 on IGF-I and long-R3-IGF-I-stimulated proliferation of L6 myogenic cells
J Cell Physiol 2004
View sourceImportant research notice
Not for human consumption. This product is sold exclusively for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the U.S. Food and Drug Administration.
Any literature referenced on this page is provided for bibliographic reference only. It is not a description of this product, nor a claim about what it does.
By purchasing you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional requirements.
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