The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Mitochondrial Peptide
MOTS-C
- Mitochondrial ORF of the 12S rRNA type-c
A 16-amino-acid peptide (MRWQEMGYIFYPRKLR) encoded by a short open reading frame within the mitochondrial 12S rRNA gene.
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Compound information
Technical specifications
Description
A 16-amino-acid peptide (MRWQEMGYIFYPRKLR) encoded by a short open reading frame within the mitochondrial 12S rRNA gene.
Molecular profile
- Type
- Mitochondrial-derived peptide
- CAS number
- 1627580-64-6
- Molecular weight
- 2174.6 g/mol
- Molecular formula
- C101H152N28O22S2
- Amino acids
- 16
Storage requirements
Lyophilized (powder)
-20°C
Reconstituted
2-8°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Reconstitute with bacteriostatic water
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Commonly held alongside this compound in the same catalog category.
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Sources & references
Published literature, listed for reference only. Nothing here describes an intended use of this product.
The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress
Cell Metab 2018
View sourceMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Nat Commun 2021
View sourceImportant research notice
Not for human consumption. This product is sold exclusively for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the U.S. Food and Drug Administration.
Any literature referenced on this page is provided for bibliographic reference only. It is not a description of this product, nor a claim about what it does.
By purchasing you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional requirements.
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