Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
Mitochondria-Targeting Peptide
SS-31
- Elamipretide MTP-131
A tetrapeptide of alternating basic and aromatic residues containing a D-arginine and the non-proteinogenic residue 2',6'-dimethyltyrosine, with a C-terminal amide.
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Compound information
Technical specifications
Description
A tetrapeptide of alternating basic and aromatic residues containing a D-arginine and the non-proteinogenic residue 2′,6′-dimethyltyrosine, with a C-terminal amide.
Molecular profile
- Type
- Aromatic-cationic mitochondria-targeting tetrapeptide
- CAS number
- 736992-21-5
- Molecular weight
- 639.8 g/mol
- Molecular formula
- C32H49N9O5
- Amino acids
- 4
Storage requirements
Lyophilized (powder)
-20°C
Reconstituted
2-8°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Reconstitute with bacteriostatic water
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Commonly held alongside this compound in the same catalog category.
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Sources & references
Published literature, listed for reference only. Nothing here describes an intended use of this product.
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin
J Am Soc Nephrol 2013
View sourceMitochondrial targeted antioxidant peptide ameliorates hypertensive cardiomyopathy
J Am Coll Cardiol 2011
View sourceImportant research notice
Not for human consumption. This product is sold exclusively for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the U.S. Food and Drug Administration.
Any literature referenced on this page is provided for bibliographic reference only. It is not a description of this product, nor a claim about what it does.
By purchasing you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional requirements.
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