LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
Dual Receptor Agonist
GLP-3 (TRZ)
- LY3298176
A synthetic 39-amino-acid peptide built on the GIP sequence with Aib at positions 2 and 13, a C-terminal amide, and a C20 fatty diacid conjugated via a linker. Studied as a dual GIP and GLP-1 receptor agonist.
Order now to ship today Weekday cutoff 2:00 PM EDT.
- Two day: est. Tue, Oct 6
- Free shipment protection
- Overnight: est. Mon, Oct 5
- Free shipping on orders over $100
- Damage protection included on every order
- Secure checkout 256-bit SSL
Compound information
Technical specifications
Description
A synthetic 39-amino-acid peptide built on the GIP sequence with Aib at positions 2 and 13, a C-terminal amide, and a C20 fatty diacid conjugated via a linker. Studied as a dual GIP and GLP-1 receptor agonist.
Molecular profile
- Type
- Dual GIP/GLP-1 receptor agonist peptide
- CAS number
- 2023788-19-2
- Molecular weight
- 4813.45 g/mol
- Molecular formula
- C225H348N48O68
- Amino acids
- 39
Storage requirements
Lyophilized (powder)
-20°C
Reconstituted
2-8°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Reconstitute with bacteriostatic water
Frequently researched together
Commonly held alongside this compound in the same catalog category.
SLU-PP-332
ERR Agonist
$60.00
GLP-2 (SM)
GLP-1 Receptor Agonist
$50.00
GLP-3 (RT)
Triple Receptor Agonist
Price range: $45.00 through $50.00
MOTS-C
Mitochondrial Peptide
$45.00
Cagrilintide
Amylin Analogue
$50.00
Adipotide
Adipose-Targeting Peptide
$60.00
AOD-9604
Growth Hormone Fragment
$50.00
5-Amino-1MQ
NNMT Inhibitor
$45.00
Sources & references
Published literature, listed for reference only. Nothing here describes an intended use of this product.
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
JCI Insight 2020
View sourceTirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue
Mol Metab 2022
View sourceImportant research notice
Not for human consumption. This product is sold exclusively for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the U.S. Food and Drug Administration.
Any literature referenced on this page is provided for bibliographic reference only. It is not a description of this product, nor a claim about what it does.
By purchasing you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional requirements.
Get started
Every research compound you need, tested before it ships.
Same-day dispatch on orders placed before the daily cutoff, with the certificate of analysis for your lot included.
Research updates from OneLab Peptides
Catalog updates, new research compounds, and quality documentation news.
For researchers and laboratories. No spam, unsubscribe anytime.
Thanks — you're on the list.