Development of Cagrilintide, a Long-Acting Amylin Analogue
Amylin Analogue
Cagrilintide
- AM833 NNC0174-0833 NN9838
A synthetic 37-amino-acid analogue of human amylin with an intramolecular disulfide bridge, a C-terminal amide, and a C20 fatty diacid acylation. Studied as an agonist at amylin and calcitonin family receptors.
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Compound information
Technical specifications
Description
A synthetic 37-amino-acid analogue of human amylin with an intramolecular disulfide bridge, a C-terminal amide, and a C20 fatty diacid acylation. Studied as an agonist at amylin and calcitonin family receptors.
Molecular profile
- Type
- Long-acting amylin analogue peptide
- CAS number
- 1415456-99-3
- Molecular weight
- 4409 g/mol
- Molecular formula
- C194H312N54O59S2
- Amino acids
- 37
Storage requirements
Lyophilized (powder)
-20°C
Reconstituted
2-8°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Reconstitute with bacteriostatic water
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Sources & references
Published literature, listed for reference only. Nothing here describes an intended use of this product.
AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors
J Pharmacol Exp Ther 2021
View sourceStructural and dynamic features of cagrilintide binding to calcitonin and amylin receptors
Nat Commun 2025
View sourceImportant research notice
Not for human consumption. This product is sold exclusively for laboratory research. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the U.S. Food and Drug Administration.
Any literature referenced on this page is provided for bibliographic reference only. It is not a description of this product, nor a claim about what it does.
By purchasing you confirm you are a qualified researcher and will handle this material in accordance with all applicable laws and institutional requirements.
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